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测试ID：mppG

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mumps Virus Antibody, IgG, Serum

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overview

亚博棋牌

对...有用
suggests clinical disorders or settings where the test may be helpful

确定个体对腮腺炎疫苗的免疫后免疫反应

以前没有免疫记录腮腺炎病毒的病毒记录的先前感染了腮腺炎病毒先前感染的记录

方法名称
一种short description of the method used to perform the test

multiplex Flow Immunoassay (MFI)

纽约州可用
我ndicates the status of NY State approval and if the test is orderable for NY State clients.

是的

报告名称
列出了测试的已发布名称的缩写或缩写版本

mumps AB，IgG，S

别名
lists additional common names for a test, as an aid in searching

mumps IgG

腮腺炎血清学

specimen Type
描述了测试验证的样品类型

血清

specimen Required
defines the optimal specimen required to perform the test and the preferred volume to complete testing

Container/Tube:

首选：血清凝胶

一种cceptable:红色顶部

specimen Volume:0.5毫升

形式

如果不以电子方式订购，请完成，打印并发送我nfectious Disease Serology Test Request(T916) with the specimen

specimen Minimum Volume
定义由测试实验室确定的提供临床相关结果所需的样品数量

0.4 mL

拒绝due To
标识可能导致样品被拒绝的样品类型和条件

严重的溶血 拒绝
Gross lipemia 拒绝
Gross icterus 拒绝
热灭活标本 拒绝

specimen Stability Information
provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

specimen Type temperature 时间 特殊容器
血清 refrigerated (preferred) 14天
Frozen 14天

对...有用
suggests clinical disorders or settings where the test may be helpful

确定个体对腮腺炎疫苗的免疫后免疫反应

以前没有免疫记录腮腺炎病毒的病毒记录的先前感染了腮腺炎病毒先前感染的记录

Clinical Information
discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

mumps病毒是paramyxoviridae病毒家族的成员，其中包括副菌病毒血清型1-4，麻疹，呼吸道合胞病毒（RSV）和Metapneumovirus。腮腺炎在未接种疫苗的个体中具有高度感染性，通常通过吸入感染的呼吸液滴或分泌而传播。大约2周的孵育期之后，症状发作通常是急性的，低级发烧，头痛和不适的前途。（1,2）唾液腺的疼痛肿大，腮腺炎的标志，大约60％，至60％。70％的感染和95％的症状患者。睾丸疼痛（提供率）发生在大约15％至30％的后假男性和腹部疼痛（卵巢炎）中发生在5％的后假妇女中。神经系统疾病（脑膜炎<10％，脑炎<1％）。

widespread routine immunization of infants with attenuated mumps virus has dramatically decreased the number of reported mumps cases in the United States. However, outbreaks continue to occur, indicating persistence of the virus in the general population.

laboratory diagnosis of mumps is typically accomplished by detection of IgM- and IgG-class antibodies to the mumps virus. However, due to the widespread mumps vaccination program, in clinically suspected cases of acute mumps infection, serologic testing should be supplemented with virus isolation in culture or detection of viral nucleic acid by polymerase chain reaction (PCR) in throat, saliva, or urine specimens.

reference Values
describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

vaccinated: Positive (> or =1.1 AI)

你nvaccinated: Negative (< or =0.8 AI)

reference values apply to all ages.

解释
provides information to assist in interpretation of the test results

积极的：

the presence of detectable IgG-class antibodies indicates prior exposure to the mumps virus through infection or immunization. Individuals testing positive are considered immune to mumps virus.

equivocal:

提交一个在10到14天内进行测试的额外样本，以证明如果最近接种疫苗或其他临床指示，请证明IgG血清转化。

消极的:

the absence of detectable IgG-class antibodies suggests no prior exposure to the mumps virus or the lack of a specific immune response to immunization.

Cautions
讨论可能导致诊断混乱的条件，包括不正确的标本收集和处理，不适当的测试选择以及干扰物质

mumps virus shares antigenic relationships with other viruses of the paramyxovirus group; therefore, serologic cross-reactions are possible, but uncommon with this test procedure.(2)

我gG-class antibodies to mumps virus may be present in serum specimens from individuals who have received blood products within the past several months, but have not been immunized or experienced past infection with this virus.

在急性感染期间抽出的血清样品可能对该病毒的IgG级抗体阴性。

supportive Data

to evaluate the accuracy of the BioPlex mumps IgG multiplex flow immunoassay (MFI), 500 prospective serum specimens were analyzed in a blinded fashion by the SeraQuest mumps IgG EIA and the BioPlex mumps IgG assay. Specimens with discordant results after initial testing were repeated by both assays during the same freeze/thaw cycle. Further discrepancies were evaluated by the mumps IgG VIDAS enzyme-linked fluorescent immunoassay (ELFA; bioMerieux, Inc). The results are summarized below:

seraQuest Mumps IgG EIA

Bioplex mumps IgG

积极的

消极的

equivocal

积极的

412

4(a)

8

消极的

3(b)

48

3

equivocal

5

6

11

(a) All 4 of these samples tested positive by VIDAS Mumps IgG ELFA

（b）这3个样品之一，由Vidas腮腺炎igG Elfa测试为阴性

sensitivity: 98.1% (412/420); 95% CI: 96.2% to 99.1%

specificity: 82.8% (48/58); 95% CI: 70.9% to 90.6%

总体百分比协议：94.2％（471/500）；95％CI：91.8％至96.0％

Clinical Reference
recommendations for in-depth reading of a clinical nature

1. Hviid A, Rubin S, Muhlemann K: Mumps. Lancet. 2008 Mar;371(9616):932-944

2. Hodinka RL, Moshal KL: Childhood infections. In: Storch GA ed. Essentials of Diagnostic Virology. Churchill Livingstone; 2000:168-178

3。litman N, Baum SG: Mumps virus. In Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:2087-2092

方法描述
describes how the test is performed and provides a method-specific reference

the BioPlex 2200 mumps IgG assay uses multiplex flow immunoassay technology. Briefly, serum samples are mixed and incubated at 37 degrees C with sample diluent and dyed beads coated with mumps antigen. After a wash cycle, antihuman-IgG antibody conjugated to phycoerythrin (PE) is added to the mixture and incubated at 37 degrees C. Excess conjugate is removed in another wash cycle and the beads are resuspended in wash buffer. The bead mixture then passes through a detector that identifies the bead based on dye fluorescence and determines the amount of antibody captured by the antigen by the fluorescence of the attached PE. Raw data are calculated in relative fluorescence intensity. Three additional dyed beads, an internal standard bead, a serum verification bead, and a reagent blank bead are present in each reaction mixture to verify detector response, the addition of serum to the reaction vessel and the absence of significant nonspecific binding in serum.(Package insert: BioPlex 2200 System MMRV IgG, Bio-Rad Laboratories: 11/30/2018)

pdFreport
指示该报告是否包含带有图表，图像或其他丰富信息的其他文档

no

day(s) Performed
概述了进行测试的日子。该领域反映了样品必须在测试实验室中才能开始测试过程的一天，并包括进行测试之前的任何标本准备和处理时间。一些测试被列为连续执行的，这意味着测定在白天多次执行。

monday through Saturday

report Available
the interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

same day/1 to 3 days

specimen Retention Time
outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

14天

performing Laboratory Location
指示执行测试的实验室的位置

罗切斯特

Fees
several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • 一种uthorized users can sign in totest Prices有关详细的费用信息。
  • Clients without access to Test Prices can contact亚搏24 hours a day, seven days a week.
  • prospective clients should contact their Regional Manager. For assistance, contact亚搏。

test Classification
provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

该测试已被美国食品药品监督管理局清除，批准或豁免，并根据制造商的说明使用。梅奥诊所以与CLIA要求一致的方式验证了绩效特征。

CPT代码信息
为确定每个测试或配置文件的适当当前程序术语（CPT）代码提供指导。列出的CPT代码反映了Mayo Clinic实验室对CPTyabo208编码要求的解释。每个实验室的责任是确定用于计费的正确CPT代码。

CPT代码由表演实验室提供。

86735

lo我nC® Information
provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

test Id 测试订单名称 订单loinc值
mppG mumps AB，IgG，S 6476-6
result Id test Result Name result LOINC Value
一种pplies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
deXG5 腮腺炎IgG抗体指数 25418-5
m你mG mumps AB，IgG，S 6476-6

测试设置资源

setup Files
test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel|pdf

样本报告
normal and Abnormal sample reports are provided as references for report appearance.

normal Reports|异常报告

SI样本报告
我nternational System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

s我normal Reports|s我异常报告